“Possible therapeutic effects of Nigella sativa and thymoquinone on COVID-19.”

“Nature itself is the best physician.” -Hippocrates

You have heard Zatik Naturals and its customers rave about the natural and affordable benefits of adding Black Seed Oil (“Nigella sativa”) to skincare and health regimens. But with Covid-19 part of our new daily lives, we wanted to cite top research and medical sources for our customers to learn first hand what the experts and their studies have learned about the benefits of Black Seed Oil on our health. Much from ancient times has been written about Nigella Sativa and her extraordinary benefits due to her active ingredient, Thymoquinone. Much continues to be published about this powerful, pure seed that is still sending waves throughout worldwide medical communities. Note that listing a study does not mean it has been evaluated by the U.S. Federal Government. The following sources and their findings are in no way associated with Zatik Naturals.


 Black Seeds - nigella sativa

Source: “Possible therapeutic effects of Nigella sativa and thymoquinone on COVID-19.” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8204995

The preliminary data of molecular docking, animal, and clinical studies propose N. sativa (Nigella sativa) and Thymoquinone the active ingredient of Nigella Sativa (TQ) might have beneficial effects on the treatment or control of COVID-19 due to antiviral, anti-inflammatory and immunomodulatory properties, as well as bronchodilatory effects. Natural products and essential oils are well recognized for their antiviral, anti-inflammatory and immuno-modulatory activities (Asif et al. 2020; Kumar et al. 2020). Turkeys fed with N. sativa (6%) had significantly lower titre of virus compared to the control group.


Nigella Sativa Flower

Nigella sativa seed has been traditionally used for the treatment of fever, infection, chest congestion, inflammation, cough, bronchitis, asthma, chronic headache, dysmenorrhoea, obesity, diabetes, flatulence, and diarrhea (Durmuskahya and Ozturk 2013; Nasir et al. 2014). The active ingredient of N. sativa seed is mainly thymoquinone (TQ) which showed anti-inflammatory effects by suppression of prostaglandins and leukotrienes as inflammatory mediators (Hajhashemi et al. 2004). Antioxidant and anti-epileptic, as well as anti-Alzheimer’s and anti-Parkinson’s disease effects of N. sativa and TQ, were previously reported (Khazdair 2015).


Nigella sativa is traditionally used for the treatment of various types of disorders including diabetes, cough, fever, eczema, bronchitis, and influenza (Ali and Blunden 2003). Pharmacological effects of N. sativa including the anti-inflammatory, antioxidant (Mohebbatia, Khazdair, Karimia et al. 2017; Bordoni et al. 2019), antimicrobial (Emeka et al. 2015), neuro-protective (Mohebbatia, Khazdairb, Hedayatia et al. 2017; Khazdair, Anaeigoudari, Hashemzehi et al. 2019), and reno-protective properties (Mohebbati et al.2017) were reported.


Source: Nigella sativa L. (Black Cumin): A Promising Natural Remedy for Wide Range of Illnesses https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6535880/

Among several medicinal plants, Nigella sativa L. (“Ranunculaceae”) has been considered one of the most treasured nutrient-rich herb in history. The maximal nutritional value of black cumin can be linked to the presence of a substantial amount of vegetable protein, fiber and minerals, and vitamins. Black cumin seeds also contain significant levels of iron, copper, zinc, phosphorus, calcium, thiamin, niacin, pyridoxine, and folic acid.


Source: “Revisiting pharmacological potentials of Nigella sativa seed: A promising option for COVID-19 prevention and cure.” https://pubmed.ncbi.nlm.nih.gov/?term=covid+black+seed+oil

“Being an available candidate in nutraceuticals, N. sativa seed oil could be immensely potential and feasible to prevent and cure COVID-19. Nigella sativa seed and its active compounds have been historically recognized as an effective herbal panacea that can establish a balanced inflammatory response by suppressing chronic inflammation and promoting healthy immune response.


The essential oil and other preparations of N. sativa seed have substantial therapeutic outcomes against immune disturbance, autophagy dysfunction, oxidative stress, ischemia, inflammation, in several COVID-19 comorbidities such as diabetes, cardiovascular disorders, Kawasaki-like diseases, and many bacterial and viral infections.


Bioactive compounds of N. sativa seed, especially Thymiquinone, α-hederin, and nigellidine, could be alternative and promising herbal drugs to combat COVID-19.


Source: “Front Line COVID-19 Critical Care Alliance (FLCCC)” https://covid19criticalcare.com/wp-content/uploads/2020/12/FLCCC-Protocols-%E2%80%93-A-Guide-to-the-Management-of-COVID-19.pdf


“Nigella Sativa have anti-viral, antimicrobial, anti-inflammatory, and immune-modulatory effects with proven safety profiles. Nigella Sativa (black cumin) and honey, used in a randomized placebo-controlled study, demonstrated that the combination of honey and Nigella sativa (HNS) hastened recovery, decreased viral shedding and reduced mortality in patients with both moderate and severe COVID-19 infection. [116].”


Nigella sativa and honey are listed in the source section 2.3 “Prevention Protocol in Children and Adolescents.”

We care about your health and wellness, and hope this data informs and educates you about nature’s potent black seed and herb. To read about the Black Seed Oil products produced by Zatik Naturals, click here.

Xo Osvanna


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